Evidence based diagnostic microbiology: has its time come?

Evidence based diagnostic microbiology: has its time come?

Harmonization: Its Time Has Come.

The importance of standardization of laboratory test results has a long history traceable to the first proficiency testing results in 1947 that demonstrated large discrepancies among results from 59 hospital laboratories (1 ). The AACC published a series of monographs in 1953– 1972 titled Standard Methods of Clinical Chemistry that promoted a single measurement procedure (MP) for a measurand. T...

Run-Time Parallelization: Its Time Has Come

Current parallelizing compilers cannot identify a significant fraction of parallelizable loops because they have complex or statically insufficiently defined access patterns. This type of loop mostly occurs in irregular, dynamic applications which represent more than 50% of all applications [20]. Making parallel computing succeed has therefore become conditioned by the ability of compilers to a...

Lung cancer screening: has its time come?

Reflecting lung cancer screening’s potential for complexity, the article in this issue by Drs. Brawley and Flenaugh points out that there are so many different solitary nodules found on the low-dose helical computerized tomography (LDCT) used for lung cancer screening that algorithms are being developed to more effectively and accurately distinguish benign lesions from malignant ones. The major...

Bioimpedance: Has Its Time Finally Come?

Bioimpedance, themeasurement of the frequency-dependent resistance to the flow of low energy electrical currents between two electrodes on or within the body, has been investigated for various medical applications for over 50 years. Applications in cardiology date back to at least 1966 and have included attempts to estimate stroke volume, cardiac output, cardiac contractility and lung fluid vol...